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NKG2C & CD94

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Cat. No. Species Product Description Structure Purity Feature
NC4-H82E3 Human Biotinylated Human NKG2C&CD94 Protein, His,Avitag™ (MALS verified)
NC4-H82E3-sds
NC4-H5258 Human Human NKG2C&CD94 Protein, Fc Tag
NC4-H5258-sds
ACRO Quality

Part of Bioactivity data

NC4-H82E3-SPR
 NKG2C & CD94 SPR

PE-Labeled Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTVLL) Tetramer Protein (Cat. No. HLU-HP2H5) immobilized on CM5 Chip can bind Biotinylated Human NKG2C&CD94, His,Avitag (Cat. No. NC4-H82E3) with an affinity constant of 21.9 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

NC4-H5258-ELISA
 NKG2C & CD94 ELISA

Immobilized Human NKG2C&CD94, Fc Tag (Cat. No. NC4-H5258) at 5 μg/mL (100 μL/well) can bind PE-Labeled Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTVLL) Tetramer Protein (Cat. No. HLU-HP2H5) with a linear range of 0.01-5 μg/mL (QC tested).

NKG2C & CD94 Molecule Synonym Name

NKG2C & CD94

NKG2C & CD94 Molecule Background

CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2C/CD159c is used as a receptor for NK cells and some cytotoxic T cells to recognize MHC class I HLA-E molecules. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

NKG2C & CD94 References

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